Those who suffer from renal failure typically undergo hemodialysis, a procedure utilizing a dialysate solution designed to remove wastes from the blood. Several chemicals often contained within the solution, specifically acetate, acetic acid, and citrate, can result in dangerous bicarbonate levels in the patient. The FDA has recently received complaints related to the presence of these chemicals in dialysate. Doctors and other health care professionals may be unaware that when metabolized, these potential sources of alkali can contribute to elevated bicarbonate levels in patients, which in turn can contribute to metabolic alkalosis, a significant risk factor associated with cardiopulmonary arrest, low blood pressure, hypokalemia, hypoxemia, hypercapnia, and cardiac arrhythmia.
According to Fresenius Medical Care North America, both the NaturaLyte Liquid and Granuflo powder product lines contain acetate, a chemical which contributes to total bicarbonate levels in patients. According to research conducted by FMCNA, increased bicarbonate levels can often lead to alkalosis, a significant risk factor associated with cardiopulmonary arrest. Considering that both powders are used in developing dialysate solutions, it is important that clinicians exercise care when treating dialysis patients so as to ensure that their bicarbonate levels are maintained at a normal level.