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Scientific Review Finds Low T Drugs Have Known Risks But No Clear Benefits

Despite the wide range of medical conditions for which testosterone supplements are prescribed, there is little evidence that these drugs actually improve health, according to a review of published clinical trial data spanning 66 years. Scientists at Georgetown University concluded that studies show that not only do these Low T drugs have known risks, including cardiovascular risks of heart attack and stroke, such drugs were unable to demonstrate their benefit.  The review was published in the scientific journal PLOS One.

Going back as far as 1950, the Georgetown scientists reviewed 156 clinical trials that studied testosterone in cardiovascular risk, sexual function, physical function, mood, or cognitive function. These were randomized controlled clinical trials – the highest standard of clinical research that involves testing a drug in large groups of people against another group that received a placebo. The researchers excluded studies that involved bodybuilding, contraceptive effectiveness, or the treatment of any condition in women or children.

Besides finding that testosterone drugs did not show consistent benefit for cardiovascular risk, sexual function, mood, or cognitive function, the scientists also concluded that these drugs offered “little evidence” that they benefited patients. Though drugmakers tout their products as treatments that can improve erectile function and libido, the review of clinical studies concluded that the drugs did neither.  Further, according to UPI, Adriane Fugh-Berman, a pharmaceutical marketing researcher at the Georgetown University Medical Center, said that despite the marketing of testosterone drugs as a way to combat the effects of aging, the evidence suggests that the drug is “not a reasonable treatment for aging.”  “Testosterone has been marketed to improve a number of conditions but for the vast majority, our review of the data shows that not one of these claims has adequate clinical trial support,” Fugh-Berman said, according to UPI.

The evidence against use of Low T drugs continues to mount. If you or a loved one has experienced a cardiac event such as a heart attack or stroke or a blood clot such as a DVT or PE after using a Low T medication, you may be entitled to compensation. Contact the Low-T lawyers at the Levensten Law Firm at www.levenstenlawfirm.com, www.androgellawyers.com or 215-545-5600 for a free consultation.

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